diff --git a/crates/ruff/resources/test/fixtures/perflint/PERF401.py b/crates/ruff/resources/test/fixtures/perflint/PERF401.py
index 304d1a6f80..86cd660d39 100644
--- a/crates/ruff/resources/test/fixtures/perflint/PERF401.py
+++ b/crates/ruff/resources/test/fixtures/perflint/PERF401.py
@@ -60,3 +60,15 @@ def f():
     for i in range(20):
         foo.fibonacci.append(sum(foo.fibonacci[-2:]))  # OK
     print(foo.fibonacci)
+
+
+class Foo:
+    def append(self, x):
+        pass
+
+
+def f():
+    items = [1, 2, 3, 4]
+    result = Foo()
+    for i in items:
+        result.append(i)  # Ok
diff --git a/crates/ruff/resources/test/fixtures/perflint/PERF402.py b/crates/ruff/resources/test/fixtures/perflint/PERF402.py
index 55f3e08cbc..b45a8c80c9 100644
--- a/crates/ruff/resources/test/fixtures/perflint/PERF402.py
+++ b/crates/ruff/resources/test/fixtures/perflint/PERF402.py
@@ -24,3 +24,22 @@ def f():
     result = {}
     for i in items:
         result[i].append(i * i)  # OK
+
+
+class Foo:
+    def append(self, x):
+        pass
+
+
+def f():
+    items = [1, 2, 3, 4]
+    result = Foo()
+    for i in items:
+        result.append(i)  # OK
+
+
+def f():
+    import sys
+
+    for path in ("foo", "bar"):
+        sys.path.append(path)  # OK
diff --git a/crates/ruff/src/rules/perflint/rules/manual_list_comprehension.rs b/crates/ruff/src/rules/perflint/rules/manual_list_comprehension.rs
index d3d4476b8f..bf04777f79 100644
--- a/crates/ruff/src/rules/perflint/rules/manual_list_comprehension.rs
+++ b/crates/ruff/src/rules/perflint/rules/manual_list_comprehension.rs
@@ -4,6 +4,8 @@ use ruff_diagnostics::{Diagnostic, Violation};
 use ruff_macros::{derive_message_formats, violation};
 use ruff_python_ast::comparable::ComparableExpr;
 use ruff_python_ast::helpers::any_over_expr;
+use ruff_python_semantic::analyze::typing::is_list;
+use ruff_python_semantic::Binding;
 
 use crate::checkers::ast::Checker;
 
@@ -112,13 +114,6 @@ pub(crate) fn manual_list_comprehension(checker: &mut Checker, target: &Expr, bo
         return;
     };
 
-    // Ignore direct list copies (e.g., `for x in y: filtered.append(x)`).
-    if if_test.is_none() {
-        if arg.as_name_expr().is_some_and(|arg| arg.id == *id) {
-            return;
-        }
-    }
-
     let Expr::Attribute(ast::ExprAttribute { attr, value, .. }) = func.as_ref() else {
         return;
     };
@@ -127,6 +122,13 @@ pub(crate) fn manual_list_comprehension(checker: &mut Checker, target: &Expr, bo
         return;
     }
 
+    // Ignore direct list copies (e.g., `for x in y: filtered.append(x)`).
+    if if_test.is_none() {
+        if arg.as_name_expr().is_some_and(|arg| arg.id == *id) {
+            return;
+        }
+    }
+
     // Avoid, e.g., `for x in y: filtered[x].append(x * x)`.
     if any_over_expr(value, &|expr| {
         expr.as_name_expr().is_some_and(|expr| expr.id == *id)
@@ -141,6 +143,25 @@ pub(crate) fn manual_list_comprehension(checker: &mut Checker, target: &Expr, bo
         return;
     }
 
+    // Avoid non-list values.
+    let Expr::Name(ast::ExprName { id, .. }) = value.as_ref() else {
+        return;
+    };
+    let bindings: Vec<&Binding> = checker
+        .semantic()
+        .current_scope()
+        .get_all(id)
+        .map(|binding_id| checker.semantic().binding(binding_id))
+        .collect();
+
+    let [binding] = bindings.as_slice() else {
+        return;
+    };
+
+    if !is_list(binding, checker.semantic()) {
+        return;
+    }
+
     // Avoid if the value is used in the conditional test, e.g.,
     //
     // ```python
diff --git a/crates/ruff/src/rules/perflint/rules/manual_list_copy.rs b/crates/ruff/src/rules/perflint/rules/manual_list_copy.rs
index 7e12dccf76..39ad7dc059 100644
--- a/crates/ruff/src/rules/perflint/rules/manual_list_copy.rs
+++ b/crates/ruff/src/rules/perflint/rules/manual_list_copy.rs
@@ -2,6 +2,8 @@ use ruff_diagnostics::{Diagnostic, Violation};
 use ruff_macros::{derive_message_formats, violation};
 use ruff_python_ast::helpers::any_over_expr;
 use ruff_python_ast::{self as ast, Arguments, Expr, Stmt};
+use ruff_python_semantic::analyze::typing::is_list;
+use ruff_python_semantic::Binding;
 
 use crate::checkers::ast::Checker;
 
@@ -79,11 +81,6 @@ pub(crate) fn manual_list_copy(checker: &mut Checker, target: &Expr, body: &[Stm
         return;
     };
 
-    // Only flag direct list copies (e.g., `for x in y: filtered.append(x)`).
-    if !arg.as_name_expr().is_some_and(|arg| arg.id == *id) {
-        return;
-    }
-
     let Expr::Attribute(ast::ExprAttribute { attr, value, .. }) = func.as_ref() else {
         return;
     };
@@ -92,6 +89,11 @@ pub(crate) fn manual_list_copy(checker: &mut Checker, target: &Expr, body: &[Stm
         return;
     }
 
+    // Only flag direct list copies (e.g., `for x in y: filtered.append(x)`).
+    if !arg.as_name_expr().is_some_and(|arg| arg.id == *id) {
+        return;
+    }
+
     // Avoid, e.g., `for x in y: filtered[x].append(x)`.
     if any_over_expr(value, &|expr| {
         expr.as_name_expr().is_some_and(|expr| expr.id == *id)
@@ -99,6 +101,25 @@ pub(crate) fn manual_list_copy(checker: &mut Checker, target: &Expr, body: &[Stm
         return;
     }
 
+    // Avoid non-list values.
+    let Expr::Name(ast::ExprName { id, .. }) = value.as_ref() else {
+        return;
+    };
+    let bindings: Vec<&Binding> = checker
+        .semantic()
+        .current_scope()
+        .get_all(id)
+        .map(|binding_id| checker.semantic().binding(binding_id))
+        .collect();
+
+    let [binding] = bindings.as_slice() else {
+        return;
+    };
+
+    if !is_list(binding, checker.semantic()) {
+        return;
+    }
+
     checker
         .diagnostics
         .push(Diagnostic::new(ManualListCopy, *range));